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1.
Health Policy Plan ; 39(Supplement_1): i131-i136, 2024 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-38253449

RESUMO

Lao People's Democratic Republic (Lao PDR) aims at graduating from least developed country status by 2026 and must increase the level of domestic financing for health. This paper examines how the government has prepared for the decline of external assistance and how donors have applied their transition approaches. Adapting a World Health Organization (WHO) framework, reflections and lessons were generated based on literature review, informal and formal consultations and focus group discussions with the Lao PDR government and development partners including budget impact discussion. The government has taken three approaches to transition from external to domestic funding: mobilizing domestic resources, increasing efficiency across programs and prioritization with a focus on strengthening primary health care (PHC). The government has increased gradually domestic government health expenditures as a share of the government expenditure from 2.6% in 2013 to 4.9% in 2019. The Ministry of Health has made efforts to design and roll out integrated service delivery of maternal, newborn, child, and adolescent health services, immunization and nutrition; integrated 13 information systems of key health programs into one single District Health Information Software 2; and prioritized PHC, which has led to shifting donors towards supporting PHC. Donors have revisited their aid policies designed to improve sustainability and ownership of the government. However, the government faces challenges in improving cross-programmatic efficiency at the operational level and in further increasing the health budget due to the economic crisis aggravated during Coronavirus disease 2019 (COVID-19). Working to implement donor transition strategies under the current economic situation and country challenges, calls into question the criteria used to evaluate transition. This criterion needs to include more appropriate indicators other than gross national income per capita, which does not reflect a country's readiness and capacity of the health system. There should be a more country-tailored strategy and support for considering the context and system-wide readiness during donor transition.


Assuntos
COVID-19 , Planejamento em Saúde , População do Sudeste Asiático , Adolescente , Criança , Humanos , Recém-Nascido , Orçamentos , COVID-19/epidemiologia , Serviços de Saúde , Laos , Planejamento em Saúde/economia
3.
PLoS One ; 17(1): e0262743, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35089957

RESUMO

The Indonesian government launched various programs to handle stunting cases, including village funds. This paper examined the effects of village fund programs and village apparatuses' capacities to combat stunting based on aggregate data at the district level in Indonesia. Using descriptive data analysis and fixed effect panel regression, we observed that village fund programs could significantly reduce Indonesia's stunting prevalence, especially outside Java. It also revealed that the increasing education of regional leaders does not necessarily positively impact leaders' skills in handling stunting. At the same time, the number of village officials has a statistically significant influence on reducing stunting prevalence. It advised that the village budget fund can support national priorities in tackling the prevalence of stunting. Furthermore, it is essential to build the capacity of the village head for increasing awareness of health activities, especially early prevention of stunting, in addition to an adequate number of officials.


Assuntos
Administração Financeira/economia , Transtornos do Crescimento/prevenção & controle , Planejamento em Saúde/economia , Planejamento em Saúde/organização & administração , População Rural/estatística & dados numéricos , Transtornos do Crescimento/epidemiologia , Planejamento em Saúde/métodos , Humanos , Indonésia/epidemiologia , Prevalência
4.
PLoS One ; 16(10): e0255231, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34610036

RESUMO

BACKGROUND: Investment Case is a participatory approach that has been used over the years for better strategic actions and planning in the health sector. Based on this approach, a District Investment Case (DIC) program was launched to improve maternal, neonatal and child health services in partnership with government, non-government sectors and UNICEF Nepal. In the meantime, this study aimed to explore perceptions and experiences of local stakeholders regarding health planning and budgeting and explore the role of the DIC program in ensuring equity in access to maternal and child health services. METHODS: This study adopted an exploratory phenomenography design with a purposive sampling technique for data collection. Three DIC implemented districts and three comparison districts were selected and total 30 key informant interviews with district level stakeholders and six focus groups with community stakeholders were carried out. A deductive approach was used to explore the perception of local stakeholders of health planning and budgeting of the health care expenses on the local level. RESULTS: Investment Case approach helped stakeholders in planning systematically based on evidence through collaborative and participatory approach while in comparison areas previous year plan was mainly primarily considered as reference. Resource constraints and geographical difficulty were key barriers in executing the desired plan in both intervention and comparison districts. Positive changes were observed in coverage of maternal and child health services in both groups. A few participants reported no difference due to the DIC program. The participants specified the improvement in access to information, access and utilization of health services by women. This has influenced the positive health care seeking behavior. CONCLUSIONS: The decentralized planning and management approach at the district level helps to ensure equity in access to maternal, newborn and child health care. However, quality evidence, inclusiveness, functional feedback and support system and local resource utilization should be the key consideration.


Assuntos
Serviços de Saúde da Criança/estatística & dados numéricos , Planejamento em Saúde/economia , Acesso aos Serviços de Saúde/estatística & dados numéricos , Serviços de Saúde Materna/estatística & dados numéricos , Participação dos Interessados , Adulto , Criança , Serviços de Saúde da Criança/economia , Pré-Escolar , Feminino , Pessoal de Saúde/estatística & dados numéricos , Humanos , Lactente , Recém-Nascido , Nascido Vivo/epidemiologia , Masculino , Serviços de Saúde Materna/economia , Pessoa de Meia-Idade , Nepal/epidemiologia
7.
Int J Health Policy Manag ; 9(11): 466-468, 2020 11 01.
Artigo em Inglês | MEDLINE | ID: mdl-32610808

RESUMO

As the coronavirus disease 2019 (COVID-19) pandemic continues to unfold there is an untold number of trade-offs being made in every country around the globe. The experience in the United Kingdom and Canada to date has not seen much uptake of health economics methods. We provide some thoughts on how this could take place, specifically in three areas. Firstly, this can involve understanding the impact of lockdown policies on national productivity. Secondly, there is great importance in studying trade-offs with respect to enhancing health system capacity and the impact of the mix of private-public financing. Finally, there are key trade-offs that will continue to be made both in terms of access to testing and ventilators which would benefit greatly from economic appraisal. In short, health economics could - and we would argue most certainly should - play a much more prominent role in policy-making as it relates to the current as well as future pandemics.


Assuntos
COVID-19/economia , Planejamento em Saúde/economia , Política de Saúde/economia , Canadá , Humanos , SARS-CoV-2 , Reino Unido
8.
Pediatr. aten. prim ; 22(85): 85-94, ene.-mar. 2020.
Artigo em Espanhol | IBECS | ID: ibc-193453

RESUMO

En el contexto generalizado de recursos limitados para financiar las intervenciones sanitarias disponibles para una población, se requieren criterios explícitos que permitan seleccionar el conjunto de prestaciones que aporten el mayor beneficio en salud posible con los recursos existentes. La evaluación económica de intervenciones sanitarias es una herramienta de análisis que compara los costes y los resultados en salud de programas sanitarios alternativos con el fin de informar sobre su eficiencia. El marco tradicional de la evaluación económica presenta algunas limitaciones para la evaluación específica de intervenciones de salud pública, como son los programas de vacunación, especialmente los destinados a la población pediátrica. Entre ellos se destacan los desafíos que presenta evaluar intervenciones donde los efectos en salud ocurren en el largo plazo, sobre poblaciones diferentes a las que se aplica la intervención, con posibles efectos adversos en población sana, con efectos intangibles considerables, con implicaciones relevantes sobre la desigualdad, y que requieren de la medición de resultados en salud en niños y niñas, así como en sus entornos. Entre las principales vías de avance para que las evaluaciones económicas sean capaces de abordar las problemáticas inherentes a los programas de vacunación en población pediátrica destacamos la posibilidad de emplear medidas de resultados capaces de captar beneficios de bienestar social más allá de las mejoras en salud individuales, así como la aplicación de los métodos que caractericen los efectos dinámicos y los altos niveles de incertidumbre cuando estos sean necesarios


In the widespread context of limited resources to fund health care interventions available to a population, explicit criteria are required to select the health care package that achieves the maximum population health with existing resources. Economic evaluation of health interventions is an analytical tool that compares the costs and health benefits of alternative health programmes with the aim to inform about their efficiency. The traditional economic evaluation framework has some limitations for the specific evaluation of public health programmes such as vaccine programmes, especially for those targeted to the paediatric population. Among these, we highlight the challenges of evaluating interventions with long-term health effects on different populations to which the intervention is applied, with possible adverse events on healthy individuals, with considerable intangible effects, with relevant implications on inequalities, and that require the quantification of health effects on children as well as their relatives. The main lines of further developments for economic evaluation to address the inherent issues of vaccine programmes for children that we highlight consist in the possibility of using outcomes measures capable of capturing social well-being benefits beyond individual health improvements, as well as the application of methods to characterise dynamic effects and high levels of uncertainty when these are needed


Assuntos
Humanos , Criança , Programas de Imunização/economia , Vacinas/economia , Controle de Doenças Transmissíveis/métodos , Análise Custo-Benefício , 16672/estatística & dados numéricos , Planejamento em Saúde/economia
9.
Rural Remote Health ; 20(1): 5495, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-32069064

RESUMO

INTRODUCTION: Iran's Health Transformation Plan (HTP) was implemented in 2014 to decrease household expenditures. The present study seeks to measure the household financial contribution to healthcare expenditures in Sistan-Baluchistan Province after the implementation of HTP. METHODS: A household survey was conducted in 2017 in Sistan-Baluchistan Province. The province is the most remote and poorest in the country and this poverty has extended to most of its main health indicators as well. About 2400 households were selected as the study samples using multistage sampling. Data were collected using the World Health Survey questionnaire. The questionnaire was designed by WHO in 2003 for assessing health system performance. Two main indicators of equity in health were measured: the percentage of households facing catastrophic health expenditure (CHE) and the Fair Financial Contribution Index (FFCI). The multiple adjusted logistic regression model was used to study the likelihood of facing CHE and to calculate the adjusted odds ratios (OR) using the model coefficients. Data were then analyzed the Statistical Package for the Social Sciences. RESULTS: The results showed that 484 (20.2%) of the households faced CHE after implementation of the HTP. The FFCI was approximately 0.7 across the province. Statistically significant relationships were observed between the chances of facing CHE and variables including place of residence (p=0.010), having members aged more than 65 years (p=0.005) and having members with disabilities and in need of care (p=0.001). There were statistically significant relationships between the chance of facing CHE and variables related to the use of health services, including the use of dental (OR=5.212), rehabilitation (OR=2.471), diagnostic and laboratory (OR=3.637), and inpatient (OR=2.511) services. CONCLUSION: Despite the implementation of HTP, a high percentage of the households faced CHE. The authorities should pay more attention to low-income and remote regions of the country; in addition, the HTP should financially cover outpatient healthcare services in an adequate manner.


Assuntos
Gastos em Saúde/estatística & dados numéricos , Planejamento em Saúde/economia , Serviços de Saúde/economia , Adulto , Idoso , Doença Catastrófica/economia , Características da Família , Feminino , Inquéritos Epidemiológicos , Humanos , Irã (Geográfico) , Masculino , Pessoa de Meia-Idade , Pobreza , População Rural
10.
Eval Program Plann ; 77: 101725, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31629248

RESUMO

In recent times, there has been an increasing drive to demonstrate value for money (VfM) for investments made in public health globally. However, there is paucity of information on practical insights and best practices that have helped implementing organisations to successfully embed VfM in practice for programming and evaluation. In this article, we discuss strengths and weaknesses of approaches that been used and insights on best practices to manage for, demonstrate, and compare VfM, using a health pooled fund programme implemented in conflict-affected South Sudan as case study supported by evidence reported in the literature while critiquing adequacy of the available approaches in this setting. An expanded and iterative process framework to guide VfM embedding for health programming and evaluation is then proposed. In doing so, this article provides a very relevant one-stop source for critical insight into how to embed VfM in practice. Uptake and scale-up of the proposed framework can be essential in improving VfM and aid effectiveness which will ultimately contribute to progress towards achieving the Sustainable Development Goals by 2030.


Assuntos
Planejamento em Saúde/economia , Financiamento da Assistência à Saúde , Cooperação Internacional , Conflitos Armados , Análise Custo-Benefício , Humanos , Avaliação de Programas e Projetos de Saúde , Alocação de Recursos/economia , Alocação de Recursos/métodos , Sudão do Sul
11.
Poult Sci ; 98(12): 6644-6658, 2019 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-31557295

RESUMO

Antimicrobial resistance is a global threat for both human and animal health. One of the main drivers of antimicrobial resistance is inappropriate antimicrobial use in livestock production. The aim of this study was to examine the technical and economic impact of tailor-made interventions, aimed at reducing antimicrobial use in broiler production. Historical (i.e., before intervention) and observational (i.e., after intervention) data were collected at 20 broiler farms. Results indicate that average daily gain and mortality generally increased after intervention, whereas feed conversion and antimicrobial use decreased. Economic performance after interventions was generally higher than before the interventions. Sensitivity analyses on price changes confirm the robustness of the findings.


Assuntos
Criação de Animais Domésticos/métodos , Anti-Infecciosos/uso terapêutico , Galinhas , Revisão de Uso de Medicamentos/estatística & dados numéricos , Criação de Animais Domésticos/economia , Animais , Revisão de Uso de Medicamentos/economia , Europa (Continente) , Planejamento em Saúde/economia , Planejamento em Saúde/estatística & dados numéricos , Avaliação de Programas e Projetos de Saúde
12.
Afr J AIDS Res ; 18(2): 138-147, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31282299

RESUMO

The contribution of civil society organisations (CSOs) to national HIV/AIDS responses in sub-Saharan African countries, with Global Health Initiatives' (GHIs) funding channelled through National AIDS Commissions (NACs), is well researched. Less well understood are the governance models and funding mechanisms being used to successfully engage CSOs in the HIV/AIDS response. Using data from government, donor, CSO and documentary sources, this article characterises the organisational principles and practices and unique funding models adopted by the Ghana AIDS Commission (GAC) to effectively and efficiently engage CSOs in the HIV/AIDS response. It found four major governance principles and practices that target: 1) strategic planning for service delivery; 2) focussed expressions of interest; 3) competitive tendering and contracting for service delivery; and 4) adoption of results-based management. It also identified three predominant funding models that illustrate the application of these guiding principles to harness the inherent strengths of CSOs to more effectively respond to HIV/AIDS, namely: 1) direct funding of locally-based CSOs; 2) funding international and national NGOs to engage local CSOs in partnership; and 3) funding umbrella organisations. These findings are significant for Ghana but they may also have relevance for other low- or middle-income countries (LMICs) that have limited experience delivering HIV/AIDS services through state-civil society partnerships, as well as broader debates on the role of donors, governments and CSOs working in partnership to fight HIV/AIDS.


Assuntos
Saúde Global/legislação & jurisprudência , Infecções por HIV/economia , Planejamento em Saúde/organização & administração , Gana , Governo , Infecções por HIV/tratamento farmacológico , Planejamento em Saúde/economia , Planejamento em Saúde/legislação & jurisprudência , Financiamento da Assistência à Saúde , Humanos , Organizações , Parcerias Público-Privadas/organização & administração
13.
Aten. prim. (Barc., Ed. impr.) ; 51(6): 359-366, jun.-jul. 2019. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-185716

RESUMO

Objetivo: Describir el uso de dispositivos sanitarios de las personas con cronicidad avanzada, cuantificando y caracterizando el coste de dicho consumo para sugerir mejoras en los modelos de atención. Diseño: Estudio observacional, analítico y prospectivo durante 3 años de una cohorte de personas con cronicidad avanzada. Emplazamiento: Tres equipos de atención primaria (EAP) de Osona, Cataluña. Participantes: Un total de 224 personas identificadas como enfermos avanzados mediante una estrategia poblacional sistemática. Mediciones principales: Edad, sexo, tipo de domicilio, trayectoria final de vida; uso, tipo y coste de los recursos en atención primaria, urgencias, por equipos de paliativos o de hospitalización (en agudos o atención intermedia). Resultados: Se realizaron una media de 1,1 ingresos al año (estancia media = 6 días), el 74% en hospitales de atención intermedia. El 93,4% del tiempo los pacientes vivieron en la comunidad, realizando un contacto semanal con el EAP (45,1% en domicilio). El coste medio diario fue 19,4euros, siendo los principales capítulos la hospitalización de atención intermedia (36,5%), la actividad EAP (29,4%) y los ingresos en agudos (28,6%). Los determinantes de menor coste serían la trayectoria fragilidad/demencia (p < 0,001), vivir en una residencia (p < 0,001) y el sobreenvejecimiento (p < 0,001). Hay ciertas diferencias en el comportamiento de los EAP en el coste global y en recursos comunitarios (p < 0,05). Conclusiones: Los consumos en hospitalización intermedia y atención primaria son más relevantes que las estancias en centros de agudos. Los contextos residencial y domiciliario son importantes para atender con efectividad y eficiencia, especialmente cuando los EAP se preparan para ello


Objective: To describe the use of health resources of people with advanced chronicity, quantifying and characterizing its cost to suggest improvements in health care models. Design: Observational, analytical and prospective study during 3 years of a cohort of people with advanced chronicity. Location: Three primary care teams (EAP) of Osona, Cataluña. Participants: 224 people identified as advanced patients through a systematic population strategy. Main measurements: Age, sex, type of home, end-of-life trajectory; use, type and cost of resources in primary care, emergencies, palliative teams or hospitalization (in acute or intermediate care). Results: Patients made an average of 1.1 admissions per year (average stay = 6 days), 74% in intermediate care hospitals. They lived in the community 93.4% of time, carrying out 1 weekly contact with the EAP (45.1% home care). The average daily cost was 19.4 euros, the main chapters were intermediate care hospitalizations (36.5%), EAP activity (29.4%) and admissions in acute hospitals (28.6%). Factors determining a potential lower cost are frailty/dementia as trajectory (p < 0.001), living in a nursing-home facility (p < 0.001) and over-aging (p < 0.001). There are certain differences in the behavior of the EAP related to the global cost and to community resources (p < 0.05). Conclusions: Consumption in intermediate hospitalization and primary care is more relevant than stays in acute care centers. Nursing-homes and home-care strategies are important to attend effectively and efficiently, especially when primary care teams get ready for it


Assuntos
Humanos , Doença Crônica/economia , Equipamentos e Provisões/economia , Estudos de Coortes , Modelos de Assistência à Saúde , Atenção Primária à Saúde/economia , Recursos em Saúde/economia , Estudos Prospectivos , Análise de Variância , Planejamento em Saúde/economia , Recursos em Saúde/estatística & dados numéricos
14.
Multimedia | Recursos Multimídia | ID: multimedia-3001

RESUMO

Foi publicada no dia 13 de janeiro de 2012 a Lei Complementar n. 141, que regulamenta a Emenda Constitucional n. 29, com a definição sobre a aplicação de recursos em ações e serviços de saúde por parte da União, estados e Distrito Federal, e municípios brasileiros. Ela também esclarece critérios de rateio de recursos e transferências para a saúde, assim como para fiscalização, avaliação e controle das despesas nas três esferas de governo e revoga dispositivos das leis n. 8.080, de setembro de 1990, e n. 8.698, de julho de 1993. Tendo em vista a importância da Lei para a gestão do SUS, o CONASS promoveu uma reunião ampliada entre a sua Câmara Técnica de Gestão e Financiamento (CTGF), o Ministério da Saúde e especialistas em orçamento público, no dia 6 de março de 2012, em Brasília/DF.


Assuntos
Administração em Saúde Pública/economia , Planejamento em Saúde/economia , Gestão em Saúde
15.
Med Anthropol Q ; 33(4): 539-556, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31134634

RESUMO

Since the early 1990s, the World Bank and Inter-American Development Bank have led efforts advocating the use of economic tools in setting priorities for health spending in poor countries. But while these powerful global health institutions present economic management as the key to improving health, they often fail to implement even their own policies requiring the use of economic tools for health project planning. In these institutions, economic tools operate beyond application for decision-making, becoming simultaneously a site of tensions regarding sovereignty and sites of enjoyment for economists at development bank headquarters. This article traces the ways that economic tools are both deployed and left aside across development bank networks, and in the process are productive of both affect and power. Attention to frictions in the use of economic tools ought to help motivate more just global health governance, taking into account political considerations that are built into expert practice.


Assuntos
Países em Desenvolvimento/economia , Saúde Global , Planejamento em Saúde/economia , Antropologia Médica , Saúde Global/economia , Saúde Global/etnologia , Guiana/etnologia , Humanos , Política , Fatores Socioeconômicos
16.
Multimedia | Recursos Multimídia | ID: multimedia-2550

RESUMO

Apresentação do Diretor do Fundo Nacional de Saúde, Antonio Carlos Rosa de Oliveira Junior, realizada na oficina do CONASS sobre a PRT GM/MS n. 3992/17


Assuntos
Planejamento em Saúde/economia , 16949 , Portarias , 50207
17.
Implement Sci ; 14(1): 37, 2019 04 18.
Artigo em Inglês | MEDLINE | ID: mdl-30999936

RESUMO

BACKGROUND: Collaborative care is an evidence-based program for treating depression in primary care. We sought to expand this model by recruiting clinics interested in incorporating community partners (i.e., community-based organizations (CBO) and/or family members) in the care team. Seven sites implemented evidence-based collaborative care programs with community partners while collecting information on costs of implementing and sustaining programs. METHODS: Sites retrospectively collected data on planning and implementation costs with technical assistance from study researchers. Sites also prospectively collected cost of care activities over a 1-month period once the program was implemented to determine resources needed to sustain programs. Personnel salary costs were adjusted, adding 30% for benefits and 30% for administrative overhead. RESULTS: The programs implemented varied considerably in staffing, involvement of care partners, and allocation of costs. Total planning and implementation costs varied from $39,280 to $60,575. The largest implementation cost category involved workflow development and ranged from $16,325 to $31,375 with the highest costs in this category attributed to the most successful implementation among clinic-CBO programs. Following implementation, cost per patient over the 1-month period ranged from $154 to $544. Ongoing strategic decision-making and administrative costs, which were included in cost of care, ranged from $284 to $2328 for the month. CONCLUSIONS: Sites implemented collaborative care through differing partnerships, staffing, and related costs. Costs to implement and sustain programs developed in partnership are often not collected but are crucial to understanding financial aspects of developing sustainable partnerships. Assessing such costs is feasible and can inform future partnership efforts.


Assuntos
Continuidade da Assistência ao Paciente/economia , Comportamento Cooperativo , Depressão/terapia , Planejamento em Saúde/economia , Equipe de Assistência ao Paciente/economia , Atenção Primária à Saúde/economia , Idoso , Idoso de 80 Anos ou mais , Redes Comunitárias , Família , Feminino , Humanos , Ciência da Implementação , Masculino , Pessoa de Meia-Idade , Desenvolvimento de Programas , Avaliação de Programas e Projetos de Saúde , Washington
18.
PLoS One ; 13(12): e0208297, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30532135

RESUMO

OBJECTIVE: The New Rural Cooperative Medical Scheme (NCMS) is a universal healthcare coverage plan now covering over 98% of rural residents in China, first implemented in 2003. Rising costs in the face of modest gains in health and financial protections have raised questions about the cost-effectiveness of the NCMS. METHODS: Using the most recent estimates of the NCMS's health and economic consequences from a comprehensive review of the literature, we conducted a cost-effectiveness analysis using a Markov model for a hypothetical cohort between ages 20 and 100. We then did one-way sensitivity analyses and a probabilistic sensitivity analysis using Monte Carlo simulations to explore whether the incremental cost-effectiveness ratio (ICER) falls below 37,059 international dollars [Int$], the willingness-to-pay (WTP) threshold of three times per capita GDP of China in 2013. FINDINGS: The ICER of the NCMS over the lifetime of an average 20-year-old rural resident in China was about Int$71,480 per quality-adjusted life year (QALY) gained (95% confidence interval: cost-saving, Int$845,659/QALY). There was less than a 33% chance that the system was cost-saving or met the WTP threshold. However, the NCMS did fall under the threshold when changes in the program costs, the risk of mortality and hypertension, and the likelihood of labor force participation were tested in one-way sensitivity analyses. CONCLUSION: The NCMS appears to be economically inefficient in its current form. Further cost-effectiveness analyses are warranted in designing insurance benefit packages to ensure that the NCMS fund goes toward health care that has a good value in improving survival and quality of life.


Assuntos
Análise Custo-Benefício , Planejamento em Saúde/economia , Adulto , China , Feminino , Humanos , Masculino , Cadeias de Markov , Pessoa de Meia-Idade , Modelos Teóricos , População Rural , Adulto Jovem
20.
Drug Metab Pharmacokinet ; 33(6): 243-249, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30360950

RESUMO

In this study, we aimed to understand the gap in coverage of pharmacogenomic (PGx) biomarkers between Japan and the US. PGx biomarkers (1) in the Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines; (2) that are CPIC level A or B; or (3) have US Food and Drug Administration (FDA)-approved drug labels, were determined. Subsequently, their coverage by US health insurance companies and the National Health Insurance (NHI) in Japan was investigated. We identified the top six health insurance companies with the largest market shares in the US and investigated the coverage for the PGx biomarkers by these health insurers, Medicare, Medicaid, and the NHI in Japan. We found that 19.9% of these biomarkers are covered by the six companies (10.0%, the CPIC guidelines; 25.1%, the FDA-approved drug labels). The coverage of somatic and germline biomarkers was respectively 86.8% and 8.5% in the US and 56.3% and 0.6% in Japan. A few germline PGx biomarkers are covered both in Japan and the US, but the coverage of both somatic and germline biomarkers was lower in Japan. Therefore, more coverage should be considered to improve patient outcomes after prescribing medications in Japan.


Assuntos
Planejamento em Saúde/estatística & dados numéricos , Cobertura do Seguro/estatística & dados numéricos , Farmacogenética/estatística & dados numéricos , Biomarcadores/análise , Tomada de Decisões , Planejamento em Saúde/economia , Humanos , Cobertura do Seguro/economia , Japão , Farmacogenética/economia , Estados Unidos
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